Nutshells

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Core ideas behind latest and curated research papers.

EpidemiologyNeurology

Road and rail noise have been associated with a 16-18% increase in risk of dementia in people over 60 years of age.

Cantuaria et al., BMJ, 8 September 2021

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Neurology

Stroke is one of the leading causes of death in the world. Treatment options such as dual antiplatelet therapy are pivotal in treating minor non-cardioembolic stroke. However, it is not well studied if dual therapy with aspirin and ticagrelor improves efficacy and safety compared to aspirin alone.

Wang et al., JAMA Neurology, 1 September 2021

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Dental Medicine

Extraction of non impacted third molar may have positive periodontal influence on neighbouring second molar, since it has led to decrease in concentration of inflammatory markers as well as microbial richness.

Tian et al., International Journal of Oral Science, 7 February 2021

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Nutrition and Obesity

People who took more than 7000 steps per day are associated with a 55-72% decrease in risk of premature mortality compared with those who took less than 7000 steps daily.

Paluch et al., JAMA Network Open, 1 September 2021

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Neurology

Atogepant, a calcitonin gene–related peptide receptor antagonist, may have potential in preventive treatment of migraines, since it was associated with greater reduction of number of migraine days per month than placebo.

Ailani et al., NEJM, 19 August 2021

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Nutrition and ObesitySport Medicine

About 30-40 minutes of moderate-to-vigorous intensity physical activity per day attenuates the association between risk of mortality and sedentary lifestyle.

Ekelund et al., British Journal of Sports Medicine, 31 December 2020

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NeurologySport Medicine

Neurodegenerative diseases are more frequent among professional soccer players than in the general population, especially among defenders and players with longer career length.

Russell et al., JAMA Neurology, 1 September 2021

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Oncology

Measuring tumor-derived cell-free DNA from the blood, followed by evaluation of clinical risk factors and a CT scan detected 94% of patients with various stages and subtypes of lung cancer.

Mathios et al., Nature Communications, 20 August 2021

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Cardiology

Patients with hypertension who are climbing stairs on a daily basis may have better vascular smooth muscle function compared to those who are not climbing stairs.

Yamaji et al., Hypertension Research, 16 July 2021

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NeurologyNeuroscience

Age-related memory impairment associated with increased GABAergic inhibition may be restored by applying treatment which will target perineuronal nets and restore chondroitin 6-sulphate levels.

Yang et al., Molecular Psychiatry, 16 July 2021

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